Alzheimer’s Society

Project Title: Novel consequences of mitochondrial beta-amyloid in Alzheimer’s disease

In this fascinating piece of research at the University of St Andrews, PhD student Zoe Allen, under the supervision of Professor Gunn-Moore, is working towards developing potential therapies to help the brain continue using glucose as its energy source, rather than switching to other, less efficient sources, which can result in the deterioration of brain cell function seen in Alzheimer’s disease.

Developing treatments that target this could allow brain cells to be more resistant to other changes within the brain during Alzheimer’s disease.

The results from this project will provide further understanding of some of the changes that occur during Alzheimer’s disease, allowing the research team to build a more comprehensive picture of the disease, and give hope to thousands of people with dementia that improved treatments can be found in the future.


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